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Baseline and postoperative C-reactive protein levels predict long-term survival after lung metastasectomy

Annals of Surgical Oncology Jan 10, 2019

Pastorino U, et al. - In view of the prognostic value of the level of C-reactive protein (CRP) in the blood at diagnosis in different primary tumors, researchers investigated the predictive ability of baseline (CRP0) and 3rd postoperative day (CRP3) levels for long-term survival of patients undergoing lung metastasectomy. They analyzed a total of 846 consecutive patients who underwent the first pulmonary resection for lung metastases between January 2003 and December. Cumulative 5-year survival of 57% and 43% was noted for patients with low CRP levels and high CRP levels, respectively; 62% vs 50% for epithelial tumors, and 51% vs 34% for sarcomas. Data thereby suggest the value of baseline and postoperative CRP levels in predicting survival of patients with resectable lung metastases.

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