Khaytin I, Tapia IE, Xanthopoulos MS, et al. - In this retrospective study involving children with obstructive sleep apnea syndrome (OSAS), researchers sought to analyze the use of auto-titrating continuous positive airway pressure [CPAP] devices (autoCPAP) as an alternative to CPAP titration. They assumed that autoCPAP-derived pressures (P_MEAN, P_PEAKMEAN, P₉₀) would be comparable to titration polysomnography [PSG] pressure (PPSG). The sample consisted of OSAS children initiated on autoCPAP between 2007 and 2017 who used autoCPAP for at least 2 hours per night and who had adequate titration PSG. Of the 110 children started on autoCPAP, 44 [age (median (IQR)) was 13.01 (9.98, 16.72) years] have met requirements for inclusion. Median regression analysis showed that autoCPAP-derived pressures remained significant predictors of PPSG after adjusting for patient features like age, gender, obesity status. No significant interactions were found between these patient characteristics and autoCPAP-derived pressures. Findings indicated that autoCPAP-derived pressures correlate with the titration PSG derived pressures. The outcomes suggested that autoCPAP can be used in the pediatric population and can assess pressures that are similar to the titration pressures.