Korhonen P, et al. - This trial incorporated an inquiry of the incidence and risk factors of asthma and atopic dermatitis by seven years of age after early-term (ET) (37⁺⁰-38⁺⁶ weeks), full-term (FT) (39⁺⁰-40⁺⁶ weeks), late-term (LT) (41⁺⁰-41⁺⁶ weeks), and especially post-term (PT) (≥42 weeks) birth. An early-term birth was disclosed to be a predictor of asthma. A link was illustrated between PT birth with atopic dermatitis. The strategies that could reduce the risk of later asthma included counseling against smoking and following strict indications for planned ET deliveries and cesarean sections.

Methods

• An examination was carried out of 965,203 infants born between 1991 and 2008 in ET, FT, LT, and PT groups.
• Data extraction was performed from national health databases with regard to asthma medication reimbursement and hospital visits for atopic dermatitis.

Results

• As per the yielded data, the frequencies of asthma medication reimbursement in the ET, FT, LT, and PT groups were 4.5%, 3.7%, 3.3%, and 3.2%, respectively.
• Hospital visits attributable to atopic dermatitis were most frequently noted PT birth.
• Compared with FT births, ET births illustrated a tie-up with an increased risk of asthma (adjusted odds ratio (aOR), 95% confidence interval (CI) 1.20, 1.17-1.23), while LT (aOR, 95%CI 0.91, 0.89-0.93) births and PT (aOR, 95%CI 0.87, 0.83-0.92) births decreased this risk.
• It was found that the PT birth (aOR, 95%CI 1.06, 1.01-1.10) speculated atopic dermatitis.
• The most relevant risk factors for asthma included male sex, ET birth, smoking during pregnancy and birth by elective cesarean section, from a standpoint of the population.
• Male sex, first delivery, birth in a level II hospital and birth by cesarean section were disclosed to be the most relevant risk factors for atopic dermatitis.