Kaikkonen JE, Jula A, Viikari JSA, et al. - This study was attempted to explore the relationships between serum standardized fatty acid (FA) percentages and cardiometabolic outcomes. Researchers applied cross-sectional (n = 2,187–2,200 subjects, age 24–39 years old, women 54%) and 10-year prospective data (n = 975–1,414 subjects) from the Young Finns Study. They applied logistic regression models to estimate ORs per SD increase in FAs. The results of this study indicated that in Finnish adults, high serum percentages of total SFAs and MUFAs and low PUFAs, and also several specific FAs, predict future unfavorable cardiometabolic outcomes. PUFAs, including linoleic and docosahexaenoic acids, were inversely associated with obesity; γ-linolenic acid was positively linked with obesity. In age- and sex-adjusted models for insulin resistance, MUFAs and oleic acid were positively, and PUFAs, especially linoleic acid, were inversely linked with HOMA-IR. Palmitic acid, MUFAs, and oleic acid were positively linked with high BP, while PUFAs, n–6 (omega-6) PUFAs, and linoleic acid were inversely linked. High palmitic and low linoleic acid percentages were the most consistent predictors for incident fatty liver, in fully-adjusted models.