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Associations of gestational cardiovascular health with pregnancy outcomes: The hyperglycemia and adverse pregnancy outcome study

American Journal of Obstetrics and Gynecology Aug 08, 2020

Perak AM, Lancki N, Kuang A, et al. - Researchers here investigated if and how gestational cardiovascular health—formally characterized by a combination of five metrics (body mass index, blood pressure, lipids, glucose, and smoking)—is associated with adverse maternal and newborn outcomes. From the Hyperglycemia and Adverse Pregnancy Outcome Study, they assessed data of 2,230 mother-newborn dyads from six countries. They estimated the mean total gestational cardiovascular health score of 8.5 (of 10). All ideal metrics were reported in 35.7% and 2+ poor metrics in 7.8%. In fully adjusted models, lower risks for preeclampsia, unplanned primary cesarean section, and newborn birthweight > 90 th percentile, sum of skinfolds > 90 th percentile, and insulin sensitivity < 10 th percentile, were identified in correlation with raise in cardiovascular health score (more favorable). Findings here suggest reduced risks for several adverse pregnancy outcomes in association with more favorable cardiovascular health at 24-32 weeks’ gestation.

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