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Associations between the SHARE frailty phenotype and common frailty characteristics: Evidence from a large Danish population study

BMJ Open Oct 31, 2019

Jacobsen KK, et al. - In this registry-based cross-sectional study of 7,327 individuals aged 50+ years in the Danish municipalities of Lolland and Guldborgsund, researchers examined relationships between a frailty phenotype and frailty features well known from the literature. Nearly 6.5%, 46.7%, and 46.9% had ≥ 3 frailty components (frail), 1–2 components (prefrail) and none (non-frail), respectively. Those who were frail were elderly and more likely female vs those who were non-frail or prefrail. A stepwise reduction in educational level, and in self-evaluated health with rising frailty status, and a stepwise rise in hardship in making ends meet, number of hospital contacts and mortality with rising frailty status was noted. In contrast with people who were non-frail, among those who were prefrail or frail, mortality was greater. Thus, on the basis of these findings, the Lolland-Falster Health Study frailty evaluation was recognized as a valid instrument exhibiting the similar features as other validated frailty measures about relationships with gender, age, income insufficiency, education, comorbidity, self-evaluated health, morbidity and mortality.
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