Associations between sleep apnea and subclinical carotid atherosclerosis: The Multi-Ethnic Study of Atherosclerosis
Stroke Dec 11, 2019
Zhao YY, Javaheri S, Wang R, et al. - Researchers used multivariable linear and logistic regression models in a large multiethnic population sample to study the connections of snoring and several measurements of sleep apnea (SA) with subclinical carotid atherosclerosis. They enrolled 1,615 candidates (mean age was 68 years) from examination 5 (2010–2013) of the MESA study (Multi-Ethnic Study of Atherosclerosis). Using high-resolution B-mode ultrasound, carotid atherosclerosis was measured. Among younger but not older people, greater hypoxemia was related to increased carotid intima-media thickness. Greater hypoxemia was linked to increased carotid intima-media thickness in blacks in evaluating race-specific results. According to findings, an association was found between sleep disturbances and subclinical carotid atherosclerosis in both men and women, especially in those < 68 years of age. For carotid plaque and carotid intima-media thickness, the mechanisms underlying the link between SA and carotid atherosclerosis can vary.
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