Lyu B, Hansen KE, Jorgenson MR, et al. - Using the Wisconsin Allograft Recipient Database, researchers analyzed adult kidney transplant recipients (KTRs) (n = 1,774) with at least one eligible bone mineral density (BMD) measurement at least 3 months post-transplantation, to determine the impact of proton pump inhibitor (PPI) on osteoporosis in KTRs. They evaluated links between use of PPI and histamine-2 receptor antagonist at 3 months post-transplantation and subsequent slope of T-score. Experts reported that a PPI was used at 3 months post-transplantation in 1,478 (83.3%) participants. Findings revealed no link between PPI use and an increased rate of BMD loss in KTRs. Backing earlier observations, findings of this study revealed no significant impact of PPI use on bone mineral loss.