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Associations between prenatal cannabis exposure and childhood outcomes: Results from the ABCD study

JAMA Sep 27, 2020

Paul SE, Hatoum AS, Fine JD, et al. - As cannabis use is increasing among pregnant women, researchers sought to ascertain if and how prenatal exposure to cannabis influences child outcomes. They conducted a cross-sectional analysis of 11,489 children (655 exposed to cannabis prenatally) using data from baseline session of the ongoing longitudinal Adolescent Brain and Cognitive Development Study. Findings suggest correlation of prenatal cannabis exposure after maternal knowledge of pregnancy with greater offspring psychopathology characteristics (ie, psychotic-like experiences [PLEs] and internalizing, externalizing, attention, thought and, social problems), sleep problems, and body mass index, as well as lower cognition and gray matter volume. In view of these findings, they emphasize discouraging cannabis use during pregnancy.

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