Iida Y, et al. - The correlation between parafoveal microcirculatory status and foveal pathomorphology were discerned in this trial, in eyes with macular edema (ME) secondary to retinal vein occlusion (RVO). A quantitative analysis could be conducted of the parafoveal AEV, via adaptive optics scanning laser ophthalmoscopy in eyes with retinal vein occlusion macular edema. A reduction or an increase in parafoveal AEV possibly served as a clinical marker for the resolution or development/progression of macular edema respectively.