Johansen MC, Mosley TH, Knopman DS, et al. - Three hundred six nondemented candidates (ranged from 67 to 88 years) from the ARIC study had florbetapir positron emission tomography and 2D echocardiography (echo) to test the assumption that Aβ (β-amyloid), a core pathology of Alzheimer disease, will be correlated with subclinical cardiac structure and function echocardiogram indices. The data presented in this work showed a significant connection between a marker of left ventricular structure and elevated florbetapir standardized uptake value ratio, identified using positron emission tomography. Continuing prospective work will help establish whether improvements in cardiac structure and function are either preceding or occurring at the same time as an amyloid deposition.