Kim ED, et al. - Researchers performed a cross-sectional study to quantify the associations of estimated glomerular filtration rate (eGFR) and albumin-creatinine ratio (ACR) with continuous pulse wave velocity (PWV) and elevated PWV (in the highest quartile), using multiple linear and logistic regression models, respectively, in 3424 Atherosclerosis in Communities (ARIC) Study participants aged 66 to 90 years during 2011 to 2013. They observed an independent association of both lower eGFR and higher ACR with measures of central arterial stiffness, with stronger associations for ACR over eGFR. Overall, central arterial stiffness may be an important pathophysiologic phenotype of vascular disease in chronic kidney disease.