Jung W, et al. - Two thousand six hundred eighty-two participants (1,124 men and 1,528 women) aged ≥19 years from The Korean National Health and Nutrition Examination Survey were included by the researchers to assess the association between lead, cadmium and mercury exposure and hyperuricemia in the Korean general population. In comparison to those without hyperuricemia, subjects with hyperuricemia had higher blood lead and cadmium levels. A positive association of lead and cadmium exposure with serum uric acid levels in a dose-response manner in the nationally representative Korean population was observed. Blood cadmium levels had a positive correlation with increased risk for hyperuricemia particularly in men, especially more apparent in cotinine-verified non-smokers. Also, an incremental trend of hyperuricemia in context to lead exposure was observed, how it was not statistically significant. Hence, to interpret the observed association and public health strategies, in order to diminish heavy metal exposure, further studies are necessary for decreasing the potentially harmful effects of hyperuricemia.