de Wit AE, et al. – Via performing a prospective cohort study, researchers explored the correlation between oral contraceptive use and depressive symptoms, ascertained if this relationship is influenced by age, and determined which particular symptoms may be related to oral contraceptive use. The study sample consisted of 1,010 adolescent girls followed up for 9 years, conducted from September 1, 2005, to December 31, 2016. According to findings, 16-year-old oral contraceptive users reported higher concurrent depressive symptom scores relative to their non-oral contraceptives counterparts. In particular, oral contraceptive users reported more crying, eating issues, and hypersomnia compared with non-users. Monitoring for depressive symptoms in adolescents who use oral contraceptives is important because it can affect their quality of life and put them at risk for nonadherence.