Chan MTV, et al. - In this prospective cohort study, researchers intended to determine if there is an association between obstructive sleep apnea (OSA) and 30-day risk of cardiovascular complications following major noncardiac surgery. In the analysis, 1218 patients were included among a total of 1364 patients recruited for the study. Data reported that the composite outcome rate for postoperative cardiovascular events (myocardial injury, cardiac death, congestive heart failure, thromboembolism, atrial fibrillation, and stroke) among those with OSA vs no OSA was 21.7% vs 14.2%, a statistically significant difference. The difference, however, was only significant for the severe OSA subgroup. Investigators observed that unrecognized severe OSA was significantly linked to increased risk of 30-day postoperative cardiovascular complications among at-risk adults undergoing major non-cardiac surgery. No significant interaction effects with type of anesthesia, use of postoperative opioids, and supplemental oxygen therapy on perioperative outcomes were noted.