Association of thyroid status prior to transition to end-stage renal disease with early dialysis mortality
Nephrology Dialysis Transplantation Dec 09, 2019
You AS, Sim JJ, Kovesdy CP, et al. - In order to determine if mortality after dialysis initiation could be influenced by thyroid status in the pre-end-stage renal disease (ESRD) period, researchers performed this study utilizing the national Veterans Affairs database. They focused on the link of pre-ESRD serum thyrotropin (TSH) concentrations averaged over the 1-year prior to dialysis (‘prelude’) period with all-cause death in the first year after dialysis initiation in US veterans with chronic kidney disease. In expanded case-mix Cox models, higher mortality was observed in relation to TSH levels >5.0 mIU/L among 15,335 patients in the 1-year prelude cohort. They noted similar results for TSH > 5.0 mIU/L and mortality in the 2- and 5-year cohorts. Overall, a dose-dependent link between higher pre-ESRD TSH levels > 5.0 mIU/L and post-ESRD mortality was revealed among new ESRD patients.
Go to Original
Only Doctors with an M3 India account can read this article. Sign up for free or login with your existing account.
4 reasons why Doctors love M3 India
-
Exclusive Write-ups & Webinars by KOLs
-
Daily Quiz by specialty
-
Paid Market Research Surveys
-
Case discussions, News & Journals' summaries