Secemsky EA, et al. - In this nationwide, multicenter retrospective cohort analysis of Centers for Medicare and Medicaid Services beneficiaries, researchers assessed all-cause mortality in relation to femoropopliteal artery revascularization with drug-coated devices (drug-eluting stent or drug-coated balloon) vs non-drug-coated devices (bare metal stent or uncoated percutaneous transluminal angioplasty balloon). This study included 16,560 patients treated at 1,883 hospitals with mean (SD) age 72.9 years. Of these, 5,989 participants (36.2%) underwent revascularization with drug-coated devices. The participants were followed up for a median duration of 389 days (interquartile range, 277-508 days). After femoropopliteal artery revascularization with drug-coated devices vs non–drug-coated devices, all-cause mortality did not increase in this study. There was no connection between drug-coated devices and mortality following multivariable adjustment.