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Association of social contact with dementia and cognition: 28-year follow-up of the Whitehall II cohort study

PLoS Medicine Sep 06, 2019

Sommerlad A, et al. - Via a retrospective analysis of 10,228 participants from the Whitehall II longitudinal prospective cohort study, which included employees (aged 35–55 at baseline evaluation; 1985-1988) of London civil service departments who were followed to 2017, experts investigated the correlation of social contact with subsequent incident dementia and cognition with 28 years’ follow-up. Higher frequency of social contact at age 60 years was related to a lower risk of developing dementia, and this correlation was associated with social contact with friends rather than relatives. Furthermore, more common midlife social contact was related to greater subsequent cognitive performance, with cognitive variations between those with high and low social contact frequency maintained during an average of 15 years of cognitive follow-up. Thus, findings from this study suggested a protective influence of social contact against dementia and that more common contact bestows greater cognitive reserve; however, it is possible that the capability to maintain more social contact could be a marker of cognitive reserve.

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