Winer JR, Deters KD, Kennedy G, et al. - Findings suggested an association of both short and long sleep durations with worse outcomes for older adults, such as greater amyloid β [Aβ] burden, greater depressive symptoms, higher BMI, and cognitive decline, highlighting the value of maintaining adequate sleep.

• It was a cross-sectional study.

• The 4,417 candidates in the study involved 2,618 women (59%) and had a mean (SD) age of 71.3 (4.7) years.

• Self-reported shorter sleep duration was linearly correlated with higher Aβ burden, and short sleep duration was related to reduced cognition that was mostly in memory domains.

• There was no difference in Aβ between the long and normal sleep duration groups.

• Short and long sleep durations, however, were associated with higher BMI, depressive symptoms, and daytime napping when compared with normal sleep duration.

• Long sleep duration was linked to poor performance across multiple cognitive domains.