Association of SARS-CoV-2 test status and pregnancy outcomes
JAMA Nov 11, 2020
Ahlberg M, Neovius M, Saltvedt S, et al. - Pregnant women in labor who were infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were compared with those uninfected via assessing all women presenting in labor at Karolinska University Hospital, Stockholm, Sweden, from March 25 to July 24, 2020. Among a total of 2,682 patients presenting in labor, 156 (5.8%) were identified as SARS-CoV-2 positive (142 [91%] at admission and 14 [9%] during pregnancy). Observations revealed a higher prevalence of preeclampsia and lower prevalence of induction of labor in correlation with SARS-CoV-2 test positivity among individuals in labor. Although primarily a respiratory infection, COVID-19 also has systemic effects that may resemble preeclampsia. In line with results of 2 previous studies using comparators, there was no increased prevalence of preterm birth. Apgar scores and birth weight for gestational age did not differ between groups which is similar to that observed in a US study. Other accumulating data have already cleared that COVID-19 is less severe in pregnancy relative to the 2 previous coronavirus infections: severe acute respiratory syndrome–related coronavirus (SARS) and Middle East respiratory syndrome–related coronavirus (MERS). However, reports of pregnant persons requiring critical care, and other reports of both mother and infant deaths have been identified in association with COVID-19.
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