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Association of sarcopenia and body composition with outcomes after liver resection for tumors

JAMA Sep 27, 2020

Berardi G, Antonelli G, Colasanti M, et al. - Researchers examined whether sarcopenia influence the risk of 90-day morbidity after liver resection for malignant tumors. They conducted a cohort study of 234 patients undergoing liver resection for malignant tumors at San Camillo Forlanini Hospital, Rome, Italy; these patients were assessed for their muscle mass and strength using the skeletal muscle index (SMI) on preoperative computed tomographic scans and the handgrip strength test, respectively. Outcomes suggested sarcopenia to be linked with a higher rate of 90-day morbidity, a longer hospital stay, and a higher readmission rate. In addition, there was independent correlation of sarcopenia with the risk of 90-day morbidity. Based on findings, they emphasize measuring muscle mass and strength before liver resection for malignant tumors to detect patients with sarcopenia to reduce the risk of morbidity.

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