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Association of prealbumin levels with contrast-induced acute kidney injury in elderly patients with elective percutaneous coronary intervention

Clinical Interventions in Aging Apr 25, 2018

You ZB, et al. - In geriatric patients aged≥75 years, who underwent elective percutaneous coronary intervention (PCI) between January 2012 and December 2015, researchers determined the association of pre-procedural prealbumin levels with contrast-induced acute kidney injury (CI-AKI) and long-term outcomes. They used multivariable logistic regression and Cox proportional hazard regression analyses to find out the independent risk factors for CI-AKI and long-term mortality. Based on the receiver operating characteristic analysis, 185.5 mg/L was defined as the optimal cutoff value of prealbumin for detecting CI-AKI, with 62.7% sensitivity and 70.4% specificity. Overall, pre-procedural levels of prealbumin were shown to be independently related to an increased risk of CI-AKI and long-term mortality.
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