Wang SM, et al. - In this long-term prospective Chinese cohort study, researchers studied the association of plasma vitamin C concentration to total and cause-specific mortality in 948 subjects (473 males and 475 females) aged 53–84 years. They accrued 551 deaths from sample collection through 2016, including 141 from cancer, 170 from stroke and 174 from heart diseases. The analysis of vitamin C was performed by using season-specific quartiles, as a continuous variable and as a dichotomous variable based on sufficiency status (normal >28 µmol/L vs low ≤28 µmol/L). They used Cox proportional hazards models to estimate HRs and 95% CIs. Findings demonstrated an association between higher plasma vitamin C concentration and lower total mortality, heart disease mortality and cancer mortality. These data confirm that adequate vitamin C is important to human health.