Eggerstedt M, Stenson KM, Ramirez EA, et al. - Researchers sought to determine how multimodal analgesia vs traditional narcotic-based analgesics influence narcotic use and pain control at discharge and in the immediate postoperative period after free flap reconstructive surgery. In this cohort study, they included 28 patients receiving multimodal analgesia and 37 controls receiving traditional narcotic-based analgesics. Observations revealed lower morphine-equivalent doses administered postoperatively, better perioperative Defense and Veterans Pain Rating Scale pain scores, and lower morphine-equivalent doses prescribed at discharge in correlation with the use of multimodal analgesia compared with traditional narcotic-based analgesics. A perioperative multimodal analgesia regimen is thus identified to be correlated with the decreased opioid requirement at discharge and in the immediate postoperative period and better pain control among patients undergoing free flap reconstruction in the head and neck.