Khan NF, et al. – In this case-control study using data from a large US commercial insurance company (2004-2015) that included individuals who experienced opioid overdoses (n=2,303), researchers assessed whether opioid prescriptions to family members had any correlation to overdoses among individuals who themselves did not have an opioid prescription. In all, they identified an association of former opioid dispensing to family members with individual overdose. Also, a significant dose-response relationship between increased amounts of opioids dispensed to family members and overdosing odds was observed. The investigators, therefore, concluded that a risk factor for overdose could be family member prescriptions. They suggested that further interventions may be required to focus on the expansion of opioid antagonist access, securing prescription of the opioids in the home, and educating patient in order to limit fatal overdose among family members.