Kim JY, et al. – Researchers conducted a cohort study utilizing a Korean nationwide representative sample (2004 through 2006 data) of 985 people (aged < 45 years), to determine the relationship between obstructive sleep apnea (OSA) and affective disorders. During a 9-year follow-up period, the overall incidence of affective disorder (eg, depression and anxiety) was higher in among individuals with OSA vs controls. In those with OSA, the adjusted HRs for depression and anxiety were higher in females vs males with OSA. The authors concluded that further investigations is required to validate their findings and, if validated, future studies should examine the nature of the observed connection between OSA and affective symptoms, including potential causality.