Vasim I, et al. - Researchers examined the link between obesity phenotypes and markers of subclinical myocardial injury in 3,423 participants without known cardiovascular events (CVD) from NHANES-III. Four obesity phenotypes—metabolically healthy non-obese (MHNO; reference), metabolically unhealthy non-obese (MUNO), metabolically healthy obese (MHO), and metabolically unhealthy obese (MUO)—were taken into consideration, and multivariable logistic regression models were used to assess the links. Higher odds of subclinical myocardial injury (SC-MI) were observed in relation to MUO vs MHNO; this link was stronger in men vs women but was consistent in subgroups stratified by age and race. Relative to MHNO, no significant association of MHO or MUNO with SC-MI was identified. However, in the MUNO group, a trend towards higher odds of SC-MI was observed. Overall, worse prognosis was conferred by a combination of obesity and metabolic syndrome (MetS). Future poor outcomes may be attenuated by implementing early preventive strategies aimed at weight loss and management of MetS components.