Goh H, Kersten HM, Yoon JJ, et al. - Researchers performed this cross-sectional study to ascertain if nailfold capillary abnormalities are correlated with primary open-angle glaucoma (POAG) and the severity of glaucomatous visual field (VF) loss. Eighty-three POAG cases and 40 controls were included in this analysis. Masked graders for dilated capillaries > 50 μm, crossed capillaries, tortuous capillaries, hemorrhages, avascular zones > 100 μm, capillary density, and capillary distribution were evaluated by nailfold capillaroscopy images. Logistic regression analyses of cases and controls exhibited that avascular zones, capillary density, and capillary distribution were correlated with POAG. After controlling for demographic and clinical factors, avascular zones were correlated with both mean deviation and mean central PSD, while capillary distribution was only related to mean deviation. Findings suggested an association of nailfold capillary abnormalities with POAG as well as increased global and central vision loss.