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Association of maternal exposure to persistent organic pollutants in early pregnancy with fetal growth

JAMA Pediatrics Feb 07, 2020

Ouidir M, Louis GMB, Kanner J, et al. - In this cohort study involving 2,284 low-risk pregnant women from four racial/ethnic groups (white, black, Hispanic, and Asian), researchers intended to determine if there is a connection between maternal plasma persistent organic pollutants (POPs) in early pregnancy and fetal growth and by infant gender and maternal race/ethnicity. From July 31, 2018, to June 3, 2019, data were analyzed. The data presented in this work showed a mixture of organochlorine pesticides was negatively correlated with most fetal growth measures among pregnant women with low POP levels and that mixtures of polybrominated diphenyl ethers and dioxin-like polychlorinated biphenyls were related to the decreased abdominal circumference. Although exposures may be small, there are obvious associations with fetal growth.
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