Lin LH, et al. - By retrospectively evaluating patients diagnosed with stage 3–5 chronic kidney disease (CKD) and who went underwent coronary artery angiography in Zhongda Hospital, researchers assessed the link between Lipoprotein(a) [Lp(a)] levels and the presence of coronary artery disease (CAD) and the severity of coronary artery stenosis (CAS) in these patients. They enrolled 1,003 patients in this cross-sectional study; of these, 776 were diagnosed with CAD. The CAD group displayed significantly higher Lp(a) levels than the non-CAD group. Lp(a) levels were independently associated with severe CAS after adjusting for potential confounders. Patients with stage 3–5 CKD showed independent association of higher Lp(a) levels with the presence of CAD and the severe CAS.