Goulden R, Rowe BH, Abrahamowicz M, et al. - Whether intravenous radiocontrast is associated with clinically significant kidney injury, was investigated using a study design that allows stronger causal interpretation than existing observational research. Participants were all emergency department patients aged 18 years or older receiving D-dimer testing between 2013 and 2018 in the Canadian province of Alberta. A total of 156,028 individuals were included in this quasi-experimental cohort study. Intravenous contrast exposure was shown to be related to a 0.4 mL/min/1.73 m ² decrease in estimated glomerular filtration rate up to 6 months later, which was not statistically significant nor clinically relevant. Thus, intravenous contrast administered for computed tomographic pulmonary angiogram in an emergency setting did not exert any harmful impact on renal function.