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Association of intrauterine exposure to aspirin and blood pressure at 7 years of age: A secondary analysis

BJOG: An International Journal of Obstetrics and Gynaecology Feb 19, 2019

Chen Y, et al. - Researchers sought to determine the influence of maternal aspirin use during pregnancy on childhood blood pressure via performing a secondary analysis of the Collaborative Perinatal Project, a prospective cohort study including 12 US academic medical centres between 1959 and 1976. They identified aspirin exposure in a total of 15,793 women 4 weeks before the last menstrual period or during pregnancy. Children born to mothers who were exposed to aspirin for at least 7 days during pregnancy displayed approximately 10% and 27% reduced risk of high systolic blood pressure and diastolic blood pressure, respectively at 7 years of age. Findings thus support a possible reduction in the risk of childhood blood pressure with maternal aspirin exposure.
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