Jongkhajornpong P, Ueta M, Lekhanont K, et al. - In this prospective case-control study, researchers examined the correlation of genetic polymorphisms of human leucocyte antigens (HLA) class I and II genes with acetaminophen-related Steven-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) who developed severe ocular complications (SOC) in the Thai population. The sample consisted of 20 unrelated Thai acetaminophen-related SJS/TEN patients with SOC and 60 Thai healthy volunteers, selected at three university hospitals in Bangkok, Thailand, from September 2014 to August 2019. Findings suggested a strong association of HLA-B*44:03 with acetaminophen-related SJS/TEN patients who developed SOC in the Thai population. Furthermore, they also found moderate to strong associations with HLA-A*33:03 and HLA-C*07:01 indicating their potential roles in SOC pathogenesis in acetaminophen-related SJS/TEN.