Xue RH, Wu DD, Zhou CL, et al. - Researchers investigated if the risk of adverse pregnancy outcomes is further increased in the presence of persistently high maternal triglyceride (mTG) levels from early to late pregnancy. Participants were women (n = 12,715) who had a singleton birth and received routine serum lipid screenings in early (9-13 weeks) as well as in late (28-42 weeks) pregnancy during May 2018 to July 2019 in an university-based maternity center. Elevated risks of preterm delivery, preeclampsia, gestational diabetes mellitus, and large for gestational age were observed in relation to raised mTG levels during early pregnancy. According to the findings, an important risk factor related to adverse pregnancy outcomes could be increased mTG levels during early pregnancy but not in late pregnancy. These data imply that improved pregnancy outcomes may be achieved via lipid screenings and preventions during early pregnancy.