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Association of gestational diabetes mellitus with neonatal respiratory morbidity

Obstetrics and Gynecology Jan 31, 2019

Werner EF, et al. - In a modern U.S. cohort, researchers examined neonatal respiratory morbidity in pregnancies with and without gestational diabetes mellitus (GDM) at imminent risk of late preterm delivery. They undertook a secondary analysis of a randomized placebo-controlled trial in which betamethasone or placebo was allocated to women with singleton pregnancies at high risk for delivery between 34 0/7 and 36 5/7 weeks of gestation. The trial enrolled 2,831 women, of these, 306 (10.8%) had GDM. Compared to women without GDM, those with GDM were significantly older and were more frequently parous and had hypertensive disorders of pregnancy. However, there were no differences regarding race, gestational age at randomization (35.6 weeks) and at delivery (36.1 weeks), and study group assignment. They noted no increased neonatal respiratory morbidity in association with maternal GDM in this study population who were at high risk for late preterm birth.
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