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Association of e-cigarette use with smoking cessation among smokers who plan to quit after a hospitalization: A prospective study

Annals of Internal Medicine Apr 05, 2018

Rigotti NA, et al. - Experts sought to examine if e-cigarette use after hospital discharge was related to subsequent tobacco abstinence among smokers who intended to quit and were advised to use evidence-based treatment. During this research, the self-reported e-cigarette use (exposure) was analyzed 1 and 3 months following discharge, along with biochemically validated tobacco abstinence (outcome) 6 months after discharge. E-cigarettes were used by more than a quarter of smokers attempting to quit, mostly to aid cessation during 3 months after hospital discharge. However, few used them regularly. A connection was brought to light between this pattern of use with less tobacco abstinence at 6 months than among smokers who did not use e-cigarettes.

Methods

  • The scheme of this research was a secondary data analysis of a randomized controlled trial.
  • It was performed at 3 hospitals.
  • The enrollment comprised of 1,357 hospitalized adult cigarette smokers who planned to stop smoking, received tobacco cessation counseling in the hospital.
  • At discharge, enrollees were randomly allocated to a tobacco treatment recommendation (control) or free tobacco treatment (intervention).
  • An analysis was carried out of the self-reported e-cigarette use (exposure) 1 and 3 months after discharge.
  • In addition, biochemically validated tobacco abstinence (outcome) was evaluated 6 months after discharge.

Results

  • E-cigarette use was reported in 28% of candidates within 3 months after discharge.
  • The 237 propensity score-matched pairs demonstrated that e-cigarette users were less likely to abstain from tobacco use at 6 months (10.1% vs 26.6%; risk difference, -16.5% [95% CI, -23.3% to -9.6%]) compared to nonusers.
  • A variation was discovered between the correlation between e-cigarette use and quitting among intervention patients, who were given easy access to conventional treatment (7.7% vs 29.8%; risk difference, -22.1% [CI, -32.3% to -11.9%]), and control subjects receiving only treatment recommendations (12.0% vs 24.1%; risk difference, -12.0% [CI, -21.2% to 2.9%]) (P for interaction=0.143).

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