Rim TH, et al. - In this population-based cohort study, researchers evaluated the annual and 5-year incidence of central serous chorioretinopathy (CSC) in South Korea in the overall population and in those who have used corticosteroid medications. At least once in 2002-2015, 90.1% of adults in South Korea received corticosteroids. This data analysis could not replicate the > 30-fold increase in the risk ratio of CSC that has been reported previously, although there was a clear difference in relative risk. The incidence of CSC in middle-aged men was estimated to be approximately 1 case per 1,000 corticosteroid users in the year after medication use. The overall incidence among those who had ever used corticosteroids was 2.5 and, in those who had never used these drugs, 3.6 per 10,000 person-years. Overall, findings supported the role of corticosteroids in CSC.