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Association of cortical stimulation–induced seizure with surgical outcome in patients with focal drug-resistant epilepsy

JAMA Neurology Jun 14, 2019

Oderiz CC, et al. - In this cohort study involving 103 subjects with focal drug-resistant epilepsy, researchers ascertained if removal of the seizure-onset zone resulting from cortical stimulation was correlated with a good surgical outcome. They noted that typical electroclinical seizures in 59 patients were caused by cortical stimulation. Findings have shown that cortical stimulation seizure induction seems to identify the epileptic generator as reliably as spontaneous seizures do. The authors suggested that this finding could lead to a more time-efficient intracranial presurgical investigation of focal epilepsy as there is less need to record spontaneous seizures.
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