Kornelius E, et al. - In this retrospective cohort study, researchers intended to determine if there is a connection between blood glucose and renal endpoints in diabetic kidney disease (DKD) individuals. The sample consisted of T2D patients (n = 345) with advanced DKD with an estimated glomerular filtration rate (eGFR) between 30-90 ml/min/1.73 m² and urine albumin-to-creatinine ratio of 300-5000 mg/g. Patients were classified into two groups according to their 1-year average HbA1c: < 7% and > 7%. Data reported that mean baseline eGFR was 58 ml/min/1.73 m² and mean albuminuria levels were 1,146 and 1,313 mg/g, respectively. Findings revealed that the risks of persistent eGFR lower than 15 ml/min/1.73 m² and doubling of serum creatinine level were comparable between two groups with aHR of 0.58 and 0.61, respectively. In advanced DKD, intensive blood sugar control did not prevent renal failure.