Raheja H, Ahuja KR, Nazir S, et al. - Researchers used the National Readmission Database to investigate how baseline chronic kidney disease (CKD) could influence in‐hospital outcomes of transcatheter mitral valve repair with MitraClip (MC). They identified all patients ≥18 years of age who received MC. There were 13,563 patients receiving MC; of those, 8,935 (65.8%) had no‐CKD, 4,152 (30.6%) suffered from CKD, and 476 (3.5%) experienced end‐stage renal disease (ESRD). Significantly higher mortality, higher incidence of bleeding, blood transfusions, and 30 day all cause readmission, was found in ESRD patients vs CKD and no‐CKD participants. Significantly higher mortality, acute kidney injury, new in‐hospital hemodialysis, blood transfusions, 30 day all cause and congestive heart failure readmissions, were observed in CKD patients vs no‐CKD. Overall, worse outcomes post-MC with higher readmission rates were reported in relation to the presence of baseline kidney disease in patients, and therefore, such a population deserves careful patient selection and follow up.