Taube M, Peltonen M, Sjöholm K, et al. - In this nonrandomized controlled trial of 4,047 individuals in the Swedish Obese Subjects study, experts examined the relationship of bariatric surgery with skin cancer (squamous cell carcinoma and melanoma) and melanoma incidence. Individuals in the surgery group underwent gastric bypass (n = 266), banding (n = 376), or vertical banded gastroplasty (n = 1,365) and the control group (n = 2,040) got the customary treatment for obesity at their primary healthcare centers. Information on cancer events was accessible for 4,042 individuals. Bariatric surgery was related to a significantly decreased risk of melanoma and the risk of skin cancer in general. The skin cancer risk decrease was not related to baseline BMI or weight, levels of insulin, glucose, lipid, and creatinine, diabetes, blood pressure, alcohol consumption, or smoking. Hence, the outcomes of this study imply that in people with obesity, bariatric surgery is related to a decreased risk of skin cancer, including melanoma.