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Association of age at myopia onset with risk of high myopia in adulthood in a 12-year follow-up of a Chinese cohort

JAMA Ophthalmology Sep 21, 2020

Hu Y, Ding X, Guo X, et al. - In this ongoing, population-based prospective cohort study involving 443 eligible candidates (247 [55.8%] female; mean [SD] age at myopia onset, 11.7 [2.0] years), researchers estimated the risk of developing high myopia in adulthood associated with a specific age at myopia onset from a data set with a 12-year annual follow-up. Among the 443 eligible candidates, 54 (12.2%) developed high myopia in adulthood. The risk substantially reduced to nearly 30% for onset at 9 years of age, 20% for onset at 10 years of age, and less than 5% for onset at 12 years or older. Such results indicate that the high myopia risk is relatively high in children with myopia onset during the early school ages. Each year of delay in the age at onset substantially decreases the risk of developing high myopia in adulthood, demonstrating the value of identifying effective prevention strategies under investigation, such as increasing outdoor time.

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