Guterman EL, Betjemann JP, Aimetti A, et al. - Researchers conducted this cross-sectional study to investigate differences in clinical outcomes and costs associated with hospitalization for status epilepticus (SE) of varying refractoriness. Among 43,988 hospitalizations for SE, 22,851 patients (51.9%) were male; the mean age was 49.9 years. Status epilepticus appears to continue to impose a significant burden on patients and the US healthcare system, with high mortality and costs that rise with disease refractoriness. Interventions that prevent SE from progressing to a more refractory state may improve outcomes and reduce costs associated with this neurologic condition.