• Profile
Close

Association between the vaginal microbiota, menopause status, and signs of vulvovaginal atrophy

Menopause Oct 29, 2018

Brotman RM, et al. – Via analyzing 87 women (aged 35-60 years), researchers delineated the composition of the vaginal microbiota in premenopausal, perimenopausal, and postmenopausal women, and examined the link between the microbiota and vulvovaginal atrophy (VVA). They identified clustering of bacterial communities into six community state types (CSTs), of which four were dominated by Lactobacillus crispatus, Lactobacillus gasseri, Lactobacillus iners, or Lactobacillus jensenii. Two (CST IV-A [characterized by Streptococcus and Prevotella] and CST IV-B [characterized by Atopobium]) had low relative abundance of Lactobacillus. Perimenopausal women displayed a higher tendency to be classified as CST IV-A or L. gasseri CST, whereas postmenopausal women were frequently classified as CST IV-A. Premenopausal women displayed a higher prevalence of CSTs dominated by L. crispatus and L. iners. The vaginal microbiota of women with mild or moderate atrophy had 25-fold greater odds of being classified as CST IV-A vs L. crispatus CST vs those of women with no VVA.

Go to Original
Only Doctors with an M3 India account can read this article. Sign up for free or login with your existing account.
4 reasons why Doctors love M3 India
  • Exclusive Write-ups & Webinars by KOLs

  • Nonloggedininfinity icon
    Daily Quiz by specialty
  • Nonloggedinlock icon
    Paid Market Research Surveys
  • Case discussions, News & Journals' summaries
Sign-up / Log In
x
M3 app logo
Choose easy access to M3 India from your mobile!


M3 instruc arrow
Add M3 India to your Home screen
Tap  Chrome menu  and select "Add to Home screen" to pin the M3 India App to your Home screen
Okay