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Association between sleep apnea and blood pressure control among blacks: Jackson Heart Sleep Study

Circulation Dec 14, 2018

Johnson DA, et al. - Researchers examined the association of sleep apnea with uncontrolled blood pressure (BP) and resistant hypertension in 913 blacks who were participants of the Jackson Heart Sleep Study, with clinic BP measurements, and anthropometry done between 2012 and 2016. Using multinomial logistic regression models, the link between obstructive sleep apnea (OSA) severity and uncontrolled BP or resistant hypertension (vs controlled BP) was determined in 664 hypertensives with a mean age of 64.0 years, with predominance of female (69.1%), obese (58.6%), and college educated (51.3%). OSA was present in 25.7%, which was untreated in 94%. Uncontrolled hypertension and resistant hypertension was seen in 48% and 14%. Findings demonstrated an association of untreated moderate or severe OSA with increased odds of resistant hypertension (2.0 times higher odds). Each standard deviation higher than <90% oxyhemoglobin saturation was related to an adjusted odds ratio for resistant hypertension of 1.25. Overall, in blacks, a possible contribution of untreated OSA to inadequate BP control was suggested.
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