Weldegiorgis TZ, et al. - In 2,764 middle-aged and elderly Chinese population (aged >50 years), researchers examined the relationship between serum 25-hydroxyvitamin D (25-[OH]D) concentrations and metabolic syndrome (MetS). In men in the MetS group, serum 25-(OH)D levels were significantly lower vs those without MetS. Among men, a negative correlation was found between the higher quartiles of serum 25-(OH)D levels and the presence of MetS. Even after adjusting for potential confounders including, age, cigarette status, alcohol use, physical activity, low-density lipoprotein, creatinine, and total serum cholesterol, the link between serum 25-(OH)D levels and the prevalence of MetS persisted. The results obtained from this cross-sectional study indicate that decreased serum 25-(OH) D level in middle-aged men was significantly linked to MetS.