Wang Z, Chan AYL, Coghill D, et al. - Prenatal exposure to antipsychotics is suggested to have no correlation with attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), preterm birth (< 37 gestational weeks), and small for gestational age (birth weight < 2 standard deviations below the mean for gestational age). However, there may be a correlation of underlying maternal psychiatric disorders with the risk of ADHD and ASD in children.

• From the Hong Kong Clinical Data Analysis and Reporting System, researchers retrieved data of children born between January 2001 and January 2015 with follow-up to December 2019 for this population-based cohort study.

• This cohort study included 411,251 mother-child pairs.

• Prenatal use of antipsychotics did not link with an increased risk of ADHD, ASD, preterm birth, and small for gestational age.

• A significantly increased risk of ADHD and ASD was evident in correlation with maternal psychiatric disorders.