Bi C, Wang L, Sun C, et al. – Via conducting a cross-sectional survey among individuals without regular insulin resistance risk factors (IRRFs; IRRF-Free, n = 2,478) and a subgroup without optimal IRRFs (IRRF-Optimal, n = 1,414), experts investigated predictors of insulin resistance (IR) targeted at the population without IRRFs. Overall, in the IRRF-Free and the IRRF-Optimal groups, the prevalence of IR was 6.9% and 5.7%, respectively. Triglyceride (TG) and waist circumference were independently related to the prevalence of IR in both the groups, where TG was positively correlated with IR. In the IRRF-Free group and the IRRF-Optimal group, the area under the receiver operating characteristic curve of TG was 0.7016 and 0.7219, and the optimal cut-off value of TG to prophesy IR was 79.5 mg/dL and 81.5 mg/dL, respectively. Hence, a relationship between TG and IR even in the normal range of TG concentration was concluded. Thus, to prognosticate the prevalence of IR in the absence of IRRFs, normal TG could be used as a significant indicator.