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Association between maternal smoking during pregnancy and offspring overweight in U.S.‐born children

Pediatric Obesity Sep 17, 2020

Smart SJ, Nikaj AN, Yu L, et al. - Using data from the Third National Health and Nutrition Examination Survey (1988‐1994), retrospectively linked to natality files, researchers sought to explore the connection between maternal smoking during pregnancy and offspring overweight, and analyze the interaction between gestational age and prenatal maternal smoking. Gestational age was preterm (< 37 weeks, n = 240) or full‐term (n = 2,125) dichotomized. A questionnaire-based interview during the National Health and Nutrition Examination Survey ascertained the smoking status during pregnancy. Data reported that the prevalence of offspring overweight and obesity combined was 17.3%. Among offspring with overweight/obesity compared with offspring with healthy weight born to non‐smoking mothers, the OR of being born to smoking mothers was 0.72 in full‐term children. After control for postnatal factors, maternal smoking during pregnancy was strongly correlated with offspring overweight and obesity in preterm births. For the prevention of obesity, preterm children of smoking mothers should be given priority.

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