Rogers A, Obst S, Teague SJ, et al. - Researchers sought to provide a comprehensive systematic review and meta-analysis of the extant literature on relationships between maternal perinatal depression and anxiety and social-emotional, cognitive, language, motor, and adaptability outcomes in offspring during the first 18 years of life. Six databases have been explored (CINAHL Complete, Cochrane Library, Embase, Informit, MEDLINE Complete, and PsycInfo) for all extant studies reporting correlations between perinatal maternal mental health problems and offspring development to March 1, 2020. Maternal perinatal depression and anxiety have been related to poorer social-emotional, cognitive, language, motor, and adaptive behavior development in offspring. Evidence indicates that perinatal depression and anxiety in mothers are negatively associated with the development of offspring and are thus important prevention and early intervention targets to promote the transition of mothers to parenthood and the health and well-being of offspring of the next generation.